Dead Cells Runes Guide Unlock Every Rune & Explore More Biomes (APK Players Edition)
Runes are one of the most important parts of Dead Cells. They decide how far you can explore, which hidden paths unlock, and what areas you can access during your runs. For its players, runes matter even more because they open shortcuts and make mobile gameplay smoother, faster, and more rewarding.
This guide explains every Rune, how to unlock them, and how they change your game experience especially if you’re playing through the game on Android.
⭐ What Exactly Are Runes in Dead Cells?
Runes are permanent abilities that stay with you even after you die.
Once you unlock a rune, it becomes part of your character forever, letting you:
- Access new biomes
- Reach secret rooms
- Use movement abilities
- Explore shortcuts
- Progress deeper into future runs
Think of runes as keys that open new areas and make each future run richer and more strategic.
⭐ 1. Vine Rune
Location: Promenade of the Condemned
Effect: Creates climbing vines at green runes
Why it’s important:
This is usually the first rune players unlock. It opens up access to vertical areas and hidden rooms. Without it, you’re stuck with limited paths and loot.
⭐ 2. Teleportation Rune
Location: Toxic Sewers
Effect: Allows teleportation through purple doors/statues
Why it’s important:
Unlocks shortcuts, hidden biomes, and important blueprint routes.
Many players consider this a “must-have” rune for faster progression.
⭐ 3. Ram Rune
Location: Ossuary
Effect: Break through ground runes / smash floors
Why it’s important:
Opens secret basements, hidden loot chambers, and access to new mid-game areas.
You’ll find tons of gold, scrolls, and blueprints locked behind Ram Rune floors.
⭐ 4. Spider Rune
Location: Slumbering Sanctuary
Effect: Wall climbing — run up walls like a ninja
Why it’s important:
This is one of the best mobility runes in the game.
You can climb surfaces, skip enemies, and chase hidden rooms that were impossible before.
⭐ 5. Challenger Rune
Location: Defeat any Elite enemy
Effect: Unlocks Daily Run Mode
Why it’s important:
Daily Run Mode gives players a fast-paced challenge that trains your reaction speed and movement — very helpful for APK players learning dodge timing.
⭐ 6. Explorer Rune
Location: Found after exploring 80% of a biome
Effect: Reveals the remaining map
Why it’s important:
Lets you see shops, scrolls, exits, and hidden rooms instantly.
After a few runs, this rune becomes a huge time-saver.
⭐ Tips to Find Runes Faster (Mobile-Friendly Advice)
- Explore every side room
- Follow green, purple, and cracked floor icons
- Challenge elites early — they drop runes
- Use fast weapons for clean exploration
- Break walls — many runes hide behind fake surfaces
- Use ranged weapons vs elites on mobile
For beginners friendly tips check out our post for beginners guide.
⭐ Conclusion
Runes are the core of progression in Dead Cells. They shape your abilities, open new biomes, and make each future run stronger and more exciting. Whether you’re climbing walls with the Spider Rune or smashing hidden floors with the Ram Rune, each unlock takes you one step closer to mastering the game.
For android players, runes make navigation smoother, faster, and far more enjoyable on mobile.
If you’re ready to unlock all runes and explore every biome, get the latest version of the game and start your journey today each rune you collect brings new possibilities.
